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Acute toxicity (Mice or rats, 1 sex, 8 groups of 8 individuals)
Chronic toxicity (rats, 2 sex, 3 doses, 2 terms (1 month + recovery), 120 animals)
Fish embryotoxicity (Incubation, assessment of embryo survival, developmental speed, teratogenicity, motor activity, light-induced fading (1 dose, 80 fish)
Carcinogenic properties (mice and rats, 2 sexes, 4 doses, 1 route of administration, 24 months for rats, 18 months for mice)
Reproductive toxicity (F1, rat, as recommended by the guide for preclinical studies)

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