Pharmacokinetic studies

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Pharmacokinetic studies, including:

Development and validation bioanalytical method for quantitative determination of a substance ( 1 biological material, HPLC) , GLP

Development and validation bioanalytical method for quantitative determination of a substance (1 biolysis material, HPLC / MS) , GLP

Pilot pharmacokinetics study (1 dose)

Bioavailability study (1 dose) , GLP

Linearity Study (3 doses, 1 animal species, HPLC) , GLP

Linearity study (3 doses, 1 animal species, HPLC / MS) , GLP

Distribution Study (per organ / tissue, HPLC) , GLP

Distribution Study (per organ / tissue, HPLC / MS) , GLP

Excretion Study (urine, feces, HPLC) , GLP

Excretion Study (urine, feces, HPLC / MS) , GLP

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