Description
Alloxan / streptozotocin diabetes (Rats, 5 groups of 10 individuals, 2 months.)Autoimmune arthritis (Mice or rats, 5 groups of 12 individuals, 1 month.)
Autoimmune encephalomyelitis (model of multiple sclerosis) (Mice, 5 groups of 15 individuals, 2 months.)
Osteoporosis (Rats, 6 groups of 12 individuals, 2 months, oophorectomy)
Reparative properties: uncomplicated skin wound in rats (3 groups of 10 individuals, 2 terms (7 and 14 days)
Reparative properties: ischemic wound (Rats, 3 groups of 10 individuals, 2 terms (7 and 14 days)
Evaluation of nootropic action (Ranking (STK), introduction in-in, ZKL, Barns test, T-maze, KPL, open field with a new object (1 dose, 40 rats)
Evaluation of anxiolytic properties in mice (Ranging, introduction in-in, KPL, conditional defensive instillation, Porsolt test (40 animals)
Evaluation of antialcohol action (Ranking (STK), introduction in-in, CPL, OP, Porsolt test, solution preference test, (1 dose, 60 rats), blood biochemistry)
Parkinson's model (5 groups of mice, 75 individuals, histology, biochemistry, behavior, MPTP model)
Anti-inflammatory effect (5 groups, 75 individuals, edema or granuloma)
Hepatoprotective effect (5 groups, 75 individuals, biochemistry, histology, carbon tetrachloride or D-galactosamine)
Acute pancreatitis (5 groups, 75 individuals, biochemistry, histology, arginine)
Acute renal failure (5 groups, 75 rats, biochemistry, histology, kidney ischemia)
Analgesic activity (5 groups, 75 individuals, 1 test)
Ischemia of the brain (stroke) (5 groups, 40 rats, histology, neurological deficit, occlusion of the middle cerebral artery)
Acute bacterial pyelonephritis (5 groups, 50 rats, biochemistry)
Evaluation of antioxidant properties (5 groups, 50 rats, biochemistry, on the background of alloxan diabetes)
Sexual function of males (sexual behavior, erection, reflexes, 3 groups of individuals)
Model of Alzheimer's disease (5 groups of rats, 50 individuals, histology, blood biochemistry, KPL, OP with new objects, OAPA, Barns labyrinth)
Violation of spermatogenesis in male rats (5 groups, 90 individuals, total testosterone, spermogram, histological examination of the testes, blood test, surgical or pharmacological model)
Endometriosis in female mice (5 groups, 50 individuals, histology)
Erectile dysfunction in rats with streptozotocin-induced diabetes (4 groups, 64 rats, diabetes induction, testing of erection and contractility, histology, biochemistry)
Angiogenic effect in the model of local ischemia of the intestine (4 groups, 40 rats, registration of the number of vessels in vivo, immunohistochemistry, histology and morphometry)
Angiogenic effect in the model of chronic ischemia of the intestine (3 groups, 30 rats, registration of the number of vessels in vivo, immunohistochemistry, histology and morphometry, biochemical and hematological examination of blood)
Study of narcogenic effects on the model of electrical brain self-stimulation (12 rats, implantation of electrodes into the brain, development of instrumental skill, behavior registration, morphological control)
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